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Transdifferentiation by Ribosome
Ribosomes are generally considered to be translational machines. Recent studies showed, it has other non-translational functions called "moon-lightning" . Ribosome can also act as a transdiffrentiation factor for differentiated cells.
Tsukushi
Secreted proteoglycan molecule Tsukushi (TSK) regulates various developmental processes, such as early body patterning and neural plate formation by interacting with major signaling pathways like Wnt, BMP, Notch etc.
Akhirin
Akhirin, a secreted factor, first discovered in chick, is expressed in the ciliary marginal zone of the eye, where it works as a heterophilic cell‐adhesion molecule. In mouse it acts as a stem cell maintenance factor in the SVZ and in the DG .
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Featured Research
Our recent publication on the function of Akhirin in neurogenesis has been selected as the Journal Volume cover.
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